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A partial listand functional classification of cytokines is shown inTable 11.1. S4 also results from ventricularvibration but, contrary to S3, the vibration is secondary to ven-tricular resistance (noncompliance) during atrial contraction
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In gen-eral, these principles apply to the consent acquisition process prior to any medicalor surgical intervention, whether it is for routine clinical management or prior toenrolment in a clinical trial.